Zovirax ACICLOVIRUM cream 5% tube 2g

Zovirax ACICLOVIRUM cream 5% tube 2g

Product Code: 8719
Availability: In Stock
$17.76USD
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the drug

active substance:1 g of cream contains 50 mg of acyclovir;

other ingredients:propylene glycol, white soft paraffin, mineral oil, cetostearyl alcohol, arlacel 165, poloxamer, sodium lauryl sulfate, Dimethicone, purified water.

The

Dosage form

Cream.

cream is a white to off-white color, homogeneous, without grains, lumps and foreign matter, with no signs of stratification.

The

the Name and address of the manufacturer

Glaxo operations UK limited, United Kingdom/Glaxo Operations UK Limited, UK.

Harmer road, Barnard castle, Durham, DL12 8DT, UK/Harmire Road, Barnard Castle, Durham, DL12 8DT, UK.

The

drug description

Antiviral agents. ATC code D06B B03.

Acyclovir is a antiviral drug that has a high activity ofin vitroagainst herpes simplex virus types I and II. The toxic effect against cells of the host organism is minimal. Getting into cells infected with the herpes virus, acyclovir phosphorylated to form an active compound-acyclovir triphosphate. The first stage of this process depends on the presence of thymidine kinase virus. Acyclovir triphosphate acts as an inhibitor and substrate for viral DNA polymerase, preventing further viral DNA synthesis without affecting normal cellular processes. Pharmacokinetic studies have shown a minimum level of systemic absorption of acyclovir after repeated topical application of the cream.

Reading

treatment of infections of lips and persons caused by herpes simplex virus (Herpes labialis).

Contra

a Hypersensitivity to aciclovir, valaciclovir, propylene glycol or other components of the cream.

appropriate safety precautions for use

Cream should be used only for the treatment of herpes on the lips and face. It is not recommended to apply the cream on the mucous membranes of the mouth, eyes and apply it to treat genital herpes. You should avoid accidentally getting the cream in your eyes.

Persons suffering from severe and recurrent manifestations of herpes labialis require medical advice. People with herpes should be warned against contact transmission of the virus to other people, especially in the presence of open lesions (for example, wash your hands before and after using the cream). It is not recommended for people with immunodeficiency. Such persons need medical advice on the treatment of any infection.

Use in pregnancy and lactation

Pregnant and breast-feeding, the drug should only be used when the use, in the opinion of the physician, outweigh the risks.

The

Ability to influence the reaction rate when driving motor transport or operating other mechanisms

No data available.

The

Children

data on the safety of the drug in children under the age of 12 years is not enough, so it is recommended to use in children aged 12 years.

Method of application and doses

the Preparation is intended for external use.

Adults and children over 12apply the cream 5 times a day at approximately 4-hour intervals, except at night. It is important to start treatment as soon as possible at the beginning of the infection, best - during the prodromal period or at the stage of erythema. You can start treatment and in the late stages - papules or blisters.

Treatment lasts at least 4 days. If healing has not occurred, you can continue treatment for up to 10 days. If the symptoms do not disappear after 10 days of treatment, the patient should consult a doctor. Wash hands before and after using the cream, and avoid excessive friction or touching the affected areas with a towel to prevent exacerbation or transmission of infection.

Overdose

after oral or local application of the whole tube of cream adverse effects were not detected because of the minimal systemic effects. In the event of suspected overdose you must seek medical help.

Side-effects

in some patients, when applying the cream may appear temporary bystroprohodyaschaya acute or burning pain. Approximately 5% of patients there was a slight drying and peeling of the skin. In a small part of patients erythema (redness) and itching were observed. Very rarely reported cases of contact dermatitis after application of the cream. During the sensitivity tests, these cases were more often associated with the components of the cream base, rather than with acyclovir. There are isolated reports of immediate hypersensitivity reactions, including angioedema, due to local use of acyclovir.

The

Interaction with other medicinal products and other forms of interaction

Interactions have been identified.

The

shelf Life

3 years.

storage Conditions

Keep at temperature not exceeding 25oC and out of reach of children. Not freeze.

The

Packaging

2 g each cream in an aluminum foil tube with a plastic twist cap. 1 tube in a cardboard box.

The

Category vacation

over the counter.

ZOVIRAX CREAM 5%

Zovirax cream 5% tube 2 g – antiviral. The medication is a whitish or white color without foreign inclusions, grains, bundles.

Structure and properties

the Active ingredient of the drug is acyclovir. Activity in vitro component is aimed at the destruction of herpes viruses. The substance does not have a harmful effect on the host cells. After getting into the infected elements, the drug is phosphorylated, and the active ingredient triphosphate acyclovir affects the genetic apparatus of the virus, destroying the infection. 

Evidence:

  • Treatment of manifestations of viral infectious diseases caused by Herpes labialis on the face and lips. 
  • Local elimination of manifestations by local action of the drug.

application

the Cream is administered to children 12 years of age and adults. Wash hands thoroughly before and after use. Apply a small layer of cream at least 5 times a day. At night not to use the most effective treatment, initiated in the early stages of the disease. The duration of therapy is at least 4 days. If necessary, extend to 10 days. If the drug does not help, be sure to consult with the doctor. Avoid using towels on the affected areas to prevent transmission. 

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