active substance:betamethasone valerate;
1 g cream/ointment/emulsion skin contains betamethasone valerate 1.22 mg
(equivalent to betamethasone 1 mg);
cetostearyl alcohol; chlorocresol; polyethylene glycol (macrogol) cetostearyl ether; white soft paraffin; sodium hydroxide mineral oil; sodium dihydrogen phosphate, dihydrate; purified water
mineral oil; lanolin; paraffin white soft;
methylparaben (E 218) of polyethylene glycol (macrogol) cetostearyl ether; cetostearyl alcohol; diglycerin; mineral oil; glycerin 85% isopropyl alcohol; citric acid monohydrate, purified water.The
Corticosteroids for use in dermatology.
ATC Code D07A C01.
treatment of dermatoses sensitive to potent GCS therapy, such as psoriasis, initial treatment of severe atopic eczema.
not recommended for occlusive dressings (gypsum, etc.).
special care should be taken when applying to the skin. To avoid preparation hit in eyes or on mucous membranes. Long-term treatment and/or use on a large surface of the skin should be avoided, as it is possible to absorb the active substance.
should not be used in the first trimester of pregnancy (see section "use during pregnancy or lactation").
Soderm, ointment/cream/emulsion skin should be applied thinly to the affected areas of the skin several times a day. With the improvement of the application frequency can be reduced.
long-term use of Soder (more than 3 months) or application of ointment on large areas (more than 20% of the body surface) Should be avoided. This also applies to the treatment of more than 10% of the body surface for more than 1 week.
After the improvement of the clinical picture is often recommended the use of weak corticosteroids.
it is Recommended to carefully monitor the development of signs and symptoms of systemic action of the drug.
the form of the preparation should be adapted to the skin type and stage of the disease.
Soderm, ointment, is the overwhelming dosage form for dry, scaly and rough skin in chronic and subacute form of the disease. Soderm cream is recommended for use with increased activity of the sebaceous glands, sputum and acute form of the disease. Soderm, skin emulsion, available in vials with nozzle-dispenser. Thus, on scalp skin emulsion can be applied directly to the treated area, not wetting your hair completely.
Do not use under occlusive dressings, as the side effects of the drug may increase.
if Soder application has been skipped.
if the drug has been missed, do not double the dose the next time it is applied.
when the Soder application is interrupted.
possible exacerbation of symptoms, in this case, you should consult a doctor.
of the skin and subcutaneous tissue
the Burning, itching, irritation, dryness, folliculitis, hypertrichosis, pustular rash, hypopigmentation, acne on the background of steroid use, resizepolicy (perioral) dermatitis,
allergic contact dermatitis
skin maceration, skin atrophy, striae, sweating, especially under occlusive dressing
Infections and infestations
|secondary infection, especially under occlusive dressing|
Tingling of the skin, seal skin, cracking skin, feeling the heat, plate peeling, patchy scaling of the skin, follicular rash, erythema, telangiectasia.
when using the product on a large surface or under an occlusive bandage, especially for a long period, it is necessary to bear in mind the possibility of developing systemic action of the drug.
hypersensitivity reactions are possible in patients with individual intolerance to the components of the drug.
Any side effects observed in the systemic use of glucocorticoids, including adrenal supression, may occur with local use of GCS.
Excessive or prolonged use of corticosteroids locally can cause inhibition of pituitary-adrenal function, leads to secondary adrenal insufficiency and hypercorticism, including Cushing's syndrome. Acute symptoms of hypercortisolism are usually reversible. With an overdose, appropriate symptomatic treatment is indicated. If necessary, the electrolyte balance correction is carried out. In the case of chronic toxic effects, gradual cancellation of GCS is recommended.
so that the safety of the use of local corticosteroids for pregnant women is not established, should not be used Soderm in the first trimester of pregnancy. The appointment of such drugs is possible only in later pregnancy, provided that the expected benefit to the expectant mother clearly exceeds the potential threat to the fetus. Preparations of this group should not be used by pregnant women in large areas, in large quantities, for long periods or under occlusive dressings.
it has not yet been found that corticosteroids can penetrate into breast milk as a result of systemic absorption with local use, so when deciding whether to stop breastfeeding or discontinue the drug, it is necessary to take into account the importance of treatment that is carried out for the mother.The
there is no clinical data on the use of the drug in children, so it is undesirable to apply it to patients of this age group.
since children have a greater body mass and surface area ratio than adults, and therefore a more active absorption of the drug, children are more at risk of inhibition of GGNZ function and development of exogenous effects of corticosteroids.
Systemic absorption of local corticosteroids, as a rule, increases with an increase in the dose of GCS, an increase in the duration of treatment and the magnitude of the treated surface of the body.
therefore, corticosteroids with high activity on large areas of the skin should be used under careful regular monitoring, as they can cause depression hypothalamic-pituitary-adrenal system (GGNZ).
In the case of oppression the drug should be lifted, the frequency of application to reduce or to transfer the patient to the drug GMP, the weak action.
GGNZ Function is usually restored after discontinuation of the drug.
in some cases, withdrawal symptoms may develop that require the addition of systemic GCS.
Soderm is transferred mostly well. However, treatment should be stopped if irritation or hypersensitivity occurs.
in the event of skin irritation or signs of hypersensitivity due to the use of Soder treatment should be discontinued and the patient to choose adequate therapy. In the presence of infection, appropriate antifungal or antibacterial agents should be prescribed. If the desired effect does not occur quickly, the use of corticosteroids must be stopped before the elimination of signs of infection.The
normally, the drug does not affect the patient's reaction speed when driving or working with other mechanisms.The
due to the presence of white soft paraffin and mineral oil as auxiliary substances, Soderm ointment can damage the structure of latex condoms and reduce their safety when used during treatment.The
Pharmacological. Betamethasone valerate is a synthetic corticosteroids for topical use.
Betamethasone exhibits high glucocorticoid activity and minimal mineralocorticoid effect.
Due to anti-inflammatory, antiallergic and vasoconstrictor effect of the local corticosteroids such as betamethasone valerate is mainly used for the treatment of dermatosis, sensitive to corticosteroid treatment.
Pharmacokinetics.corticosteroids are associated with blood plasma proteins in varying degrees. They are mainly metabolized in the liver and excreted in the urine.
Systemic absorption of topical corticosteroids is expected only under adverse conditions (long-term treatment, occlusive dressing).
cream/emulsion skin smooth white lustrous ointment of uniform consistency, yellowish-white in color.The
after opening the vial/tube, the shelf life is 6 months.
Store in a place inaccessible to children at temperature not exceeding 30 ° C.The
Cream/ointment: tube of 10 g, 25 g, 50 g, 100 g
Emulsion skin-bottle of 20 ml, 50 ml, 100 ml.The
According to the recipe.The
Arzneimittel mibe GmbH, Germany.
mibe GmbH Arzneimittel, Germany.The
M?nchenerstra?e 15 06796 Brenna, Germany.
Muenchener Str. 15 06796 Brehna, Germany.
Cream Soderm has a pronounced anti-inflammatory effect, its main active ingredient is betamethasone. Appointed drug for the treatment of the skin of the head, hairy parts thereof:
Cream Soderm should be used with caution, do not use more than twice a day, do not apply on large areas of skin and not resort to long term use. It is not recommended to use the drug for more than 1 month, cancellation should take place gradually. If necessary, the cream can be used by women during pregnancy, but under the supervision of a specialist. For the treatment of children it is better to adhere to the minimum course of use.
you Should avoid applying it to wet areas of the scalp, wounds, cracks and Golikova defeat. Apply only to dry skin. It is not necessary to use a wrap bandage, if necessary, to make them weak.
Soderm is intended for external use only, it is not recommended to use it with other local preparations.