active substance:1 g ointment contains 10 mg or 25 mg of hydrocortisone acetate
other ingredients:white soft paraffin, mineral oil, lanolin.
Dosage form. Eye ointment.The
means used in ophthalmology. Anti-inflammatory drugs. Corticosteroids. PBX code S01B A02.
Method of application and doses.
Strip ointment length of about 1 cm to lay in the conjunctival SAC several times a day. Usually, the duration of treatment should not exceed 2 weeks. Depending on the clinical picture, the effectiveness of treatment should be monitored periodically in order to determine the feasibility of prolonging or changing the therapy.
avoid contact between the tube tip and the eye or skin when applying eye ointment.
Prolonged use of ophthalmic preparations containing corticosteroids may cause irreversible cataract formation and temporary increase of intraocular pressure in some patients.
Eye ointments containing hydrocortisone slow down the healing of the damaged cornea. With the use of such drugs, there are cases of hypersensitivity reactions, including itching, burning, short-term blurred vision, as well as contact dermatitis, dermatoconjunctivitis and eczema.
With proper use of the phenomena of overdose or intoxication is not expected. Until now, there have been no cases of overdose of drugs containing hydrocortisone. So, information about the specific symptoms of overdose and its treatment is missing.
the Potential risks of using the drug by pregnant women are unknown. Pregnant women should be administered with caution after a thorough assessment of the benefits and risks of such use.
Unknown, leads local use of the drug in systemic absorption and penetration of significant amounts of hydrocortisone in breast milk. Therefore, for safety reasons during breastfeeding, the drug can be used only when the expected effect of the mother's treatment exceeds the possible risks for the child.The
children have no experience with the drug.
features of the application.
contact lenses may not be worn during treatment with an acetate hydrocortisone eye ointment.
since long - term treatment (more than 2 weeks) with ophthalmic preparations of corticosteroids can cause a reversible increase in intraocular pressure or irreversible formation of cataracts, the use of the drug for more than 2 consecutive weeks should be regularly checked intraocular pressure and the state of the cornea and lens.
in the case of diseases causing corneal thinning, the use of the drug may lead to perforation.
the use of the drug may increase the risk of fungal or viral (keratitis caused byherpes simplex) eye diseases.Lanolin, which is part of the preparation, may cause local irritation (e.g. contact dermatitis). The
after the application of the acetate hydrocortisone eye ointment, vision may temporarily deteriorate due to the formation of a film on the cornea, which leads to a decrease in the rate of reaction when driving or operating machinery.
Interaction with other medicinal products and other forms of interactions.
no Special studies of drug interactions were conducted.
Concurrent use with other drugs that can increase eye pressure (eg atropine or other anticholinergics) may lead to an additional increase in intraocular pressure in patients with predisposition.
in conjunction with the use of other local ophthalmic drugs should be kept 15-minute interval between applications, and the ointment should be applied hydrocortisone acetate least.The
the Mechanism of action of corticosteroids is still not fully clarified. It is likely that corticosteroids interact with protein receptors in the cytoplasm of sensitive cells to form a steroid-receptor complex. After the appropriate conformational changes, the steroid-receptor complex enters the nucleus, where it acts on the genetic apparatus of cells in such a way that it inhibits the synthesis of certain proteins responsible for chemotaxis and immunological reactions. In addition, due to functional changes in leukocytes and macrophages, there is an inhibition of inflammatory and allergic reactions. Anti-inflammatory efficacy of hydrocortisone is due to inhibition of phospholipase A2-the enzyme necessary for the synthesis of arachidonic acid, which is the precursor of phlogogenic substances - prostaglandins and leukotrienes. Thus, corticosteroids are effective in inflammatory processes in mesenchymal tissues caused by infections, allergens and injuries.
the degree of permeability of the acetate hydrocortisone, largely depends on the state of the cornea, increases significantly with inflammation or damage to the mucous membranes of the eye.
homogeneous yellowish-white ointment of soft consistency (in the form of suspension), free of lumps and strips.The
Do not use after the expiry date indicated on the package.
Store at a temperature not exceeding 25 ° CaboutC. keep out of reach of children.The
2.5 g eye ointment in an aluminum tube with plastic tip and cap. 1 tube in a cardboard box.The
According to the recipe.The
RUSSLEND Arzneimittel GmbH/URSAPHARM Arzneimittel GmbH.The
Industriestrasse 35 D-66129 Saarbr?cken, Germany.
Industriestrasse 35, D-66129 Saarbrucken, Germany.
Virgan eye gel 1.5 mg tuba 5 g – used in ophthalmology for the treatment of superficial keratitis in acute form, the causative agent of which was the herpes virus. The main active ingredient is ganciclovir. The gel is injected into the conjunctival SAC drop by drop. The first days of the acute form of the disease should be eye drops 5 times a day. When the corneal epithelium begins to recover, it is enough to carry out the procedure three times. The course of treatment the doctor sets individually, it is usually not less than 7 days and not more than 21 days.