1 tablet contains 192 mg Pancreatin (with an activity of at least 5000 amylolytic IU, 7000 lipolytic IU, 400 proteolytic IU)
excipients:lactose, microcrystalline cellulose, sodium croscarmellose, crospovidone, povidone, silicon colloidal dioxide, magnesium stearate
shell:polyethylene glycol, azorubine (E 122), dry mix "Acryl-eze white" containing talc, titanium dioxide (E 171), methacrylate copolymer, sodium lauryl sulfate, sodium bicarbonate, silicon dioxide.The
Tablet coated liner.
Tablets, film-coated, round in shape with a concave surface, light pink color with a weak specific smell. The cross - section view shows two layers.The
THE COMPANY"FARMEKS GROUP".
Ukraine, 08300, Kyiv region, G. . Boryspil, Shevchenko str., 100.The
means to improve digestion, including enzymes. Multienzyme preparations.
PBX Code A09A A02.
Multienzyme preparation for digestion. The composition of the drug includes the main pancreatic enzymes-lipase, ?-amylase, protease (trypsin and chymotrypsin), which have lipolytic, amylolytic and proteolytic effects, increase the splitting of proteins, carbohydrates and fats in the duodenum, proximal part of the small intestine, promotes their fuller absorption. Improves the functional state of the digestive tract and normalizes digestive processes.
Tablets have a protective shell insoluble in acidic stomach contents, which prevents the destruction of pancreatic enzymes under the action of gastric juice. Pancreatic enzymes are active only in the alkaline environment and are released from the dosage form in the alkaline environment of the small intestine, acting in the lumen of the intestine.
Enzymes that are part of the drug in the digestive tract are not absorbed, so the systemic blood flow is not detected; inactivated during hydrolysis and digested. A small part of the enzymes that have not been hydrolyzed is excreted unchanged with feces.
Hypersensitivity to Pancreatin of porcine origin and/or other components of the drug, acute pancreatitis, exacerbation of chronic pancreatitis, intestinal obstruction.
in patients with cystic fibrosis who took high doses of Pancreatin preparations, cases of narrowing of the ileocecal part of the intestine and colon (fibrous colonopathy), as well as colitis, are described, but there is no evidence of a connection between taking the drug and the occurrence of fibrous colonopathy. As a preventive measure, in order to avoid the possibility of lesions of the colon, it is recommended to control all unusual symptoms or changes in the abdominal cavity, especially when taking more than 10,000 IU of lipase/kg/day.
Children who receive long-term treatment with the drug in cystic fibrosis, should be under constant medical supervision.
with prolonged use, simultaneous administration of iron preparations is recommended.The
the Drug should be used with caution in patients with renal insufficiency, hyperuricemia, patients with Allergy to proteins of porcine origin.
the Safety of Pancreatin use during pregnancy has not been sufficiently studied.
during pregnancy and lactation, the drug is taken as directed by a physician if the expected benefit to the mother exceeds the potential risk to the fetus/child.The
has No effect.The
the Drug is recommended for use in children aged 3 years.
to be taken orally during or immediately after meals, the tablets should be swallowed whole, without chewing, with plenty of liquid (water, fruit juices). The dosage of the drug is based on the individual needs of the patient and depends on the age, degree of digestive disorders and food composition.
the Dosing in cystic fibrosis.
the Starting dose for children aged 3 to 4 years is 1000 IU of lipase/kg of body weight (1 tablet/7 kg) during each meal and for children aged 4 years - 500 IU of lipase/kg of body weight (1 tablet/14 kg) during each meal. If the body weight of the child is in the interval between the values are multiples of 7 for children from 3 to 4 years or multiples of 14 for children from 4 years, at the beginning of treatment is recommended to use a dose of the drug prescribed at a lower value of this interval (for example, when the body weight of the child 20 kg at the beginning of treatment is recommended
the Dose should be selected individually, depending on the severity of the disease, control steatorrhea and maintain proper nutritional status.
the usual dose is 2 tablets (14,000 IU of lipase) 4 times a day.
Maintenance dose for most patients should not exceed 10,000 IU of lipase/kg/day.
Dosing for other types of exocrine pancreatic insufficiency.
the Initial dose is 1-4 tablets (7000-28000 IU of lipase) with each meal. However, it is possible that some patients may need to increase the dose by 1.5-2 times or even more to eliminate steatorrhea and maintain proper nutritional status. Do not exceed the recommended dose 15000-20000 IU lipase/kg/day.
The duration of treatment can vary from a few days (if digestion is impaired through the consumption of excess food) to several months or even years (if necessary, permanent replacement therapy).
Symptoms:hyperuricosuria, hyperuricemia; in children - constipation.
Treatment:withdrawal of the drug, adequate hydration, symptomatic therapy.
from the digestive system:very rarely - nausea, vomiting, flatulence, diarrhea, discomfort in the epigastric region, changes in the nature of the chair; when applying high doses in patients with cystic fibrosis - strictures in the ileocecal Department and in the ascending colon, intestinal obstruction, constipation.
Possiblehypersensitivity reactions(including Rash, itching, sneezing, lacrimation, bronchospasm, urticaria, anaphylactic reaction), perianal irritation.The
when using the drug may reduce the absorption of iron, folic acid, reduce the hypoglycemic effect of acarbose. While the use of antacids containing calcium carbonate and/or magnesium hydroxide, tannin, alcohol-containing means decreases the effectiveness of Pancreatin.The
2 years from the date of manufacture "in bulk".
does not require special storage conditions.
keep out of reach of children.The
№ 10 № 20 (10 ? 2): there are 10 tablets in blister, 1 or 2 blisters in a cardboard box.The
over the counter.
the Medicinal product is an enzyme used for disorders in the gastrointestinal tract, in order to normalize the processes of digestion and assimilation of food. The drug contains in the composition of the main active ingredient-Pancreatin, produced under normal conditions by the pancreas. This component improves the splitting of proteins, fats and carbohydrates and facilitates their assimilation. The product is presented in the form of tablets, which are coated, resistant to acidic environment of the stomach, so the drug realizes the pharmacological effect in the walls of the small intestine. One package contains 20 tablets.
the drug should be used by swallowing, sufficient amount of water, preferably during meals. Do not chew or damage the protective shell of the tablet, to preserve the enzymes. The dose is prescribed by the attending physician. The recommended dosage of the drug is 1-4 tablets, once.