Boostrix, suspension for injection 1 dose syringe 0.5 ml with 2 needles No. 1

Boostrix, suspension for injection 1 dose syringe 0.5 ml with 2 needles No. 1

Product Code: 4672
Availability: In Stock

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COMPOSITION

active ingredients: each dose (0.5 ml) contains not less than 2 International units (IU) or 2.5 Lf (limits of flocculation) diphtheria toxoid, not less than 20 IU (5 Lf) of tetanus toxoid and detoxicating 8 mcg pertussis toxin ( PT), and 8 µg filamentosa of hemagglutinin (FHA) and 2.5 µg pertactin. Diphtheria and tetanus toxoids obtained from cultures ofCorynebacterium diphtherиаеandClostridium tetani,inactivate and purify. Components of the acellular pertussis vaccine (PT, FHA and pertactin) is prepared by growing phase I culturalBordеtella pertussis,from which the PT, FHA and pertactin extracted and purified. Diphtheria toxoid, tetanus toxoid and acellular pertussis components of the vaccine adsorbed on aluminum salts;

excipients: aluminium hydroxide, aluminium phosphate, sodium chloride, water for injection. Formaldehyde, Polysorbate 80, glycine are present in the residual amount as a consequence of the production process.

The

DOSAGE FORM.

With uspeniya for injection.

Basic physical and chemical properties:turbid liquid, which is distributed to a white precipitate and colorless supernatant (the supernatant). The residue should easily go into suspension with shaking.

BOOSTRIX- a combined vaccine for preventing diphtheria, tetanus, pertussis, consisting of purified diphtheria and tetanus toxoids, three purified antigens of the causative agent of pertussis, adsorbed on aluminum hydroxide.

BOOSTRIXmeets the requirements of the world health organization to the production of biological substances, vaccines for prevention of diphtheria and tetanus.

The

Pharmacotherapeutic groups

Combined bacterial vaccines.

The

ATC CODE

J07AJ52

The

IMMUNOLOGICAL AND BIOLOGICAL PROPERTIES

Pharmacological

The introduction of the drug according to the approved recommendations causes the formation of specific immunity against diphtheria, tetanus, pertussis. The immune response to the diphtheria, tetanus and pertussis (acellular) components of the vaccine is shown in the table below. Approximately 1 month after revaccination with vaccineBOOSTRIXobserved the following levels of seroprotection/seropositivity:

The The The The
antigen
Seroprotection/
seropositivity
Adults and adolescents
by 10 years,
at least 1690 patients
(%Vaccinated)
kids
ages 4 to 9,
low
415 patients
(%Vaccinated)
The
diphtheria
? 0.1 IU/ml *
97.2% of the
99.8%
The
tetanus
? 0.1 IU/ml *
99.0%
100.0%
The
coverage for:
The
    The
  • -Karlukovo toxoid
  • The
  • -Filamentary hemagglutinin
  • The
  • -Pertactin
? 5 IFU/ml
? 5 IFU/ml
? 5 IFU

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