1 g of cream contains acyclovir 50 mg
other ingredients:steadilyincreasing, Dimethicone 350, cetyl alcohol, white soft paraffin, mineral oil, propylene glycol, purified water.
basic physico-chemical properties:
white or almost white homogeneous cream without lumps and foreign particles, without signs of phase stratification.
Antiviral agents. Code ATC D06B B03.
Acyclovir is a antiviral drug that has a high activityin vitroagainst herpes simplex virus of types I and II. The toxic effect against cells of the host organism is minimal. Getting into cells infected with the herpes virus, acyclovir phosphorylated to form an active compound-acyclovir triphosphate. The first stage of this process depends on the presence of thymidine kinase virus. Acyclovir triphosphate acts as an inhibitor and substrate for viral DNA polymerase, preventing further viral DNA synthesis without affecting normal cellular processes.
Pharmacokinetic studies have shown a minimum level of systemic absorption of acyclovir after repeated topical application of the cream.
treatment of infections of lips and persons caused by herpes simplex virus (Herpes labialis).
Hypersensitivity to acyclovir, valacyclovir, propylene glycol or other components of the cream.
Interactions have been identified.
Cream should be used only for the treatment of herpes on the lips and face. It is not recommended to apply the cream on the mucous membranes of the mouth, eyes and apply it to treat genital herpes. You should avoid accidentally getting the cream in your eyes.
Persons suffering from very serious and recurring manifestations ofHerpes labialisrequire the advice of a doctor. People with herpes should be warned against contact transmission of the virus to other people, especially in the presence of open lesions (for example, wash your hands before and after using the cream). Not recommended for patients with immunodeficiency. Such persons need medical advice on the treatment of any infection.
to achieve the best success of treatment cream should be used already when the first signs of herpes infection (burning, itching, feeling tightness and redness). Virostatic treatment with aciccream is not advisable when the skin is covered with a crust.
Pregnant and breast-feeding, the drug should only be used when the use, in the opinion of the physician, outweigh the risks.The
No data available.
Preparation is intended for external use only.
Adults and children over 12 yearsto apply the cream 5 times a day in approximately 4-hour intervals, with the exception of night time. It is important to start treatment as soon as possible at the beginning of the infection, best - during the prodromal period or at stage of erythema. You can start treatment and in the late stages - papules or blisters.
Treatment lasts at least 4 days. If healing has not occurred, you can continue treatment for up to 10 days. If the symptoms do not disappear after 10 days of treatment, the patient should consult a doctor. Wash hands before and after using the cream and avoid excessive friction or touching the affected areas with a towel to prevent exacerbation or transmission of infection.
data on the safety of the drug in children under the age of 12 years is not enough, so it is recommended to use in children aged 12 years.
accidental oral or topical application of the entire contents of the tube of cream found no adverse effects due to minimal systemic effects. In the event of suspected overdose you must seek medical help.
in some patients, when applying the cream may appear temporary bystroprohodyaschaya acute or burning pain. Approximately 5% of patients there was a slight drying and peeling of the skin. In a small part of patients erythema (redness) and itching were observed. Very rarely reported cases of contact dermatitis after application of the cream. During the sensitivity tests, these cases were more often associated with the components of the cream base, rather than with acyclovir. There are isolated reports of immediate hypersensitivity reactions, including angioedema, due to local use of acyclovir.
Store at a temperature not exceeding 25oC.
keep out of reach of children. Not freeze.
to 2 g of cream in a tube; 1 tube in a cardboard box.
over the counter.
Salutas Pharma GmbH, Germany/Salutas Pharma GmbH, Germany.
3, gems den lageplan No. 1-5, 39171 Suelzetal, district Osterweddingen, Saxony-Anhalt, Germany/Lange Gohren 3, gemass den Lageplanen Nr. 1-5, 39171 Sulzetal, OT Osterweddingen, Saxony-Anhalt, Germany.
Acic cream 5% tuba 2 g – antiviral drug spectrum for external use, the effect of which is aimed at neutralizing the herpes virus. Tool white color, homogeneous, eliminates the presence of lumps or delamination.
Two gram of cream contains 100 mg of acyclovir. Additional components include:
Acyclovir acts as an antiviral drug, neutralizing the virus of common and herpes zoster, chicken pox. The tool is included in the viral DNA and blocks the synthesis of microorganisms. On deoxyribonucleic acid healthy cells acyclovir has minimal effect.
Infections on the skin of the face and lips caused by the herpes virus.
Cream is used to treat exclusively affected areas of the face and lips, the tool is not suitable for mucous membranes. Application it is better to start when observing the first signs of infection, but at later stages.
suitable for teenagers over twelve years old and adults. Course appointments-4-10 days. The cream is used up to five times a day at intervals every four hours. If after prolonged treatment (more than 10 days) there is no positive effect, you need to consult your doctor.